Sinner holdspublished at 20:11 BST
Sinner 6-3 2-1 Mochizuki*
Jannik Sinner eases to 40-0 as Shintaro Mochizuki lets a couple of unforced errors slip, before wrapping the game up with another big first serve.
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LIVE: Defending champion Jannik Sinner 6-3 Shintaro Mochizuki
LIVE: Third seed Felix Auger-Aliassime taken to fifth set by Alejandro Davidovich Fokina
World number one Aryna Sabalenka comprehensively beaten by Naomi Osaka
Novak Djokovic defeats Roman Safiullin in four sets to reach quarter-finals
Jessica Pegula beats Iva Jovic; 2024 champion Barbora Krejcikova knocked out by Karolina Muchova
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Sinner 6-3 2-1 Mochizuki*
Jannik Sinner eases to 40-0 as Shintaro Mochizuki lets a couple of unforced errors slip, before wrapping the game up with another big first serve.
*Sinner 6-3 1-1 Mochizuki
Groans from the crowd as Jannik Sinner misses a forehand at the net before Shintaro Mochizuki serve and volleys to perfection.
Mochizuki then secures a hold to love as Sinner smashes a forehand wide.
Decent start to the second set for the world number 151.
Hurkacz 6-3 7-6 (7-5) 6-7 (2-7) 5-7 0-0 Struff*
Elsewhere, Hubert Hurkacz has just returned to court two after leaving to receive some treatment for an injury when down advantage at 5-5 in the fourth set.
Hurkacz said he wouldn't be able to continue if he didn't get that treatment. He lost the final point of that game against Jan-Lennard Struff and has just stepped up to serve.
The Pole isn't moving great and does appear to be in discomfort and has been broken to hand over the fourth set.
Hurkacz is asking the umpire if he can leave the court to go and get changed but he's been told he can't. He's not too happy and they are going into the fifth set.
Image source, ReutersSinner 6-3 1-0 Mochizuki*
Andrew Castle
BBC Sport tennis commentator on BBC One
Shintaro Mochizuk had his chances, but Jannik Sinner holds in the opening game of this second set.
He is playing a man who was on a 30-match winning streak coming into the French Open, which creates something of a legend. I don't know how you define a great, but Sinner certainly is.
Sinner 6-3 1-0 Mochizuki*
Harry Poole
BBC Sport at Wimbledon
While he is the huge underdog here, only 150 men's players worldwide can lay claim to being better ranked than Shintaro Mochizuki.
Yet, up close, the ferocity with which Jannik Sinner is hitting the ball - the speed, the power, the precision - is just on a completely different level to his opponent entirely.
The Centre Court crowd are rallying behind Mochizuki, who continues to dig in as best as he can, but unless the qualifier can change something up it feels like there's only going to be one outcome.
Sinner 6-3 1-0 Mochizuki*
Shintaro Mochizuki goes toe to toe with Jannik Sinner in a rally but skews a forehand wide when well positioned.
Sinner then wraps the game up with an ace.
*Sinner 6-3 0-0 Mochizuki
Shintaro Mochizuki brings up break point with a powerful backhand down the line but can't make it count as Jannik Sinner nails another big first serve.
*Sinner 6-3 0-0 Mochizuki
Jannik Sinner is facing a bit of resistance here as Shintaro Mochizuki works his way to deuce.
Sinner gets out of trouble with a sixth ace of the match, but plants a backhand into the net next point.
Deuce again and some murmurs of encouragement from the crowd for Mochizuki.
*Sinner 6-3 0-0 Mochizuki
Todd Woodbridge
Former Wimbledon doubles champion on BBC One
A beautifully constructed point by Shintaro Mochizuki.
He has to start taking some risks. If there is a ball that lands a little short, he has got to take it early and come forward. I know Jannik Sinner has some terrific passing shots, but that's the only thing he can do to try to take time away from his opponent and move forward.
Otherwise, he is going to be pushed off the baseline far too quickly.
Auger-Aliassime 6-7 (4-7) 7-6 (8-6) 6-3 6-7 (2-7) 5-0 Davidovich Fokina*
Felix Auger-Aliassime runs around a second serve and hammers a forehand winner - double break secured.
The third seed is closing in on the quarter-finals again and another comfortable hold, in which he sends down ace number 24, means he can almost taste it.
Alejandro Davidovich Fokina has battled hard but the 22nd seed is surely done now?
*Sinner 6-3 0-0 Mochizuki
Image source, Getty ImagesThe crowd are encouraging Shintaro Mochizuki when they get the chance and a nice volley at the net gets their approval.
He can't build on it as a double fault gifts set point to Jannik Sinner and the Italian makes it count as Mochizuki can't get a deep forehand over the net.
It's been comfortable for Sinner so far.
Auger-Aliassime 6-7 (4-7) 7-6 (8-6) 6-3 6-7 (2-7) 3-0 Davidovich Fokina*
Felix Auger-Aliassime shakes off his disappointment from the end of that fourth set and swiftly takes control of the fifth.
The Canadian third seed holds to love and then brings up three break points. Alejandro Davidovich Fokina saves the first two but can do nothing about the third.
Auger-Aliassime proceeds to hold to love again. Break consolidated.
Sinner 5-3 Mochizuki*
Andrew Castle
BBC Sport tennis commentator on BBC One
I thought what Shintaro Mochizuki said in his pre-match interview was interesting. He said: 'He is going to try to destroy me, but it is my job to be disruptive and make him uncomfortable' - and I thought that was really smart.
If you're going to play tennis, this is a really good place to do it. This will all be big news in Japan.
Sinner 5-3 Mochizuki*
The bounce on Jannik Sinner's serve is causing a lot of problems for Shintaro Mochizuki, and the Italian top seed holds comfortably to love.
Mochizuki is now serving to stay in the first set.
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*Sinner 4-3 Mochizuki
Centre Court is treated to some tennis from a bygone era as Shintaro Mochizuki serves and volleys his way to an entertaining point.
Jannik Sinner threatens, but spoons a forehand long with a chance to take the game deuce as Mochizuki holds.
Sinner 4-2 Mochizuki*
Todd Woodbridge
Former Wimbledon doubles champion on BBC One
Wow, it is a big serve isn't it?
There really isn't much Shintaro Mochizuki can do when Jannik Sinner is just pummelling 130mph out into the corner. He hasn't even got the reach to get his racquet near it.
The forehand speed difference is 77mph compared to 64mph and the spin difference is enormous, both in favour of Sinner.
Sinner 4-2 Mochizuki*
How about that from Shintaro Mochizuki as a forehand return winner across court prompts whistles from the Centre Court crowd.
Jannik Sinner isn't phased as a couple of aces sees the defending champion get to game point and despite a double fault, he secures the hold on the next point.
It's been steady, if not spectacular, so far from Sinner.
*Auger-Aliassime 6-7 (4-7) 7-6 (8-6) 6-3 6-7 (2-7) Davidovich Fokina
Image source, Getty ImagesWe're going the distance, folks!
Felix Auger-Aliassime's forehand has completely deserted him and, having saved two match points just a few minutes ago, Alejandro Davidovich Fokina clings on and forces a fifth set.
Nearly four hours into this one and the end is still a way off.
*Sinner 3-2 Mochizuki
A couple of wayward shots from Jannik Sinner gets Shintaro Mochizuki to 30-0 before a bounce off the net doesn't work in his favour.
A wry shake of the head from Jannik Sinner, before Mochizuki recovers to see out the rest of the game.