When O'Neill moved Tottenham Hotspur 21-year-old Jamie Donley from number 10 into a central striker role last year, it appeared that a favoured starting XI had emerged some two years into the manager's second stint in charge.
Injuries that ruled the likes of goalkeeper Pierce Charles and wing-back Bradley out of multiple windows have meant that preferred version of the side has still yet to take the field together.
In the time since, competition for places has increased, most especially in the centre and right side of defence.
Such was the surplus in those areas, even in the absence of Ballard and Bradley, that Sunderland full-back Trai Hume captained the side from central midfield against Ukraine.
"I don't look at it as if they're playing out of position; I look at it as them being given an opportunity to play a position that will help me and help the team," said O'Neill.
"Terry Devlin did a great job on the left-hand side which is a position where we don't have a lot of options, so that was brilliant he could give us that.
"For me, Jamie Donley has had his best games for us as a nine, so while other people may not see him as that, I do, which is the most important thing."
Defenders Brodie Spencer and Tom Atcheson sat out Sunday's training session before Georgia, although O'Neill said it was "precautionary" in both cases.
Ethan Galbraith and Callum Marshall are both available to face the side who replaced manager Willy Sagnol with under-21 boss Ramaz Svanadze after a 1-0 defeat in the reverse fixture on 25 September.
"In the middle of a window, if you're going to make a change, the natural thing would be to promote someone from within the association," said O'Neill.
"He's probably had a number of those players at under-21 level so he knows the players extremely well.
"We've studied both subsequent games and how the team has been set out, the changes that have been made, and I think we're well prepared for what style of play or tactics Georgia will use."